Metagenomic sequencing for uveitis
Clinical Study at Moorfields Eye Hospital
Supported by a research grant from Moorfields Eye Charity we are testing a new technique called Metagenomic Sequencing in patients with Uveitis.
For many people with ocular inflammation, no cause is ever found for their disease. In some cases, an infection or infectious trigger is suspected, but currently available tests are inadequate. Metagenomic sequencing can identify almost every globally known infection (bacteria, virus, fungi, parasites) in a sample. Therefore, it has the potential to identify an infection that is causing ocular inflammation, and as a consequence may help to identify specific treatments.
This study will allow us to test the technique on ocular fluid, that has been previously optimised for brain infections by the team at Great Ormond Street Hospital. We are working closely together on this project.